Troj_Agent.JPO is a Trojan that reportedly arrives via a spammed email message.

The message purports to be a notification for a Microsoft Security Bulletin and its accompanying link pretends to be the patch/update for the vulnerability discussed in the said bulletin. Clicking this link, however, downloads a copy of this Trojan on an affected system.

It can also be dropped by other malware or downloaded by a user when visiting malicious Web sites.

This Trojan accesses certain URLs to download possibly malicious files. However, these URLs are inaccessible as of this writing.

Technical details can be found at this Trend Micro page.